We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to disease instead of building durable health, and how treating your body like your ultimate asset can change the arc of your life.

Brad Pitzele’s story moves from autoimmune arthritis and melanoma risk to a sustainable routine that restored clarity and stamina—without spending hours in a chamber or crushing workouts.

We sit down with Dr. Natasha Milinkovic, a UK physician who moved from the front lines of vascular surgery and emergency medicine to the leading edge of preventive care, to explore how lab‑grade at‑home blood testing and intelligent coaching can change outcomes before a crisis hits.

What if the most powerful “sugars” aren’t fuel at all, but messages your immune system has been waiting to hear?

Dr. Hemal Patel, Professor in the Department of Anesthesiology at UC San Diego School of Medicine, takes us on a fascinating journey into the world of mitochondria.

Unlock the secrets to a longer, healthier life with our special guest, Kevin Ellis, the Bone Coach.

We sit down with Bob Messerschmidt, an optical engineer turned Apple platform architect who helped seed Apple Health and the Apple Watch, then left to build a simple at-home device that measures ESR, a century‑old inflammation marker with fresh relevance for longevity.

Cary Kelly’s story might make you question your most basic assumptions about food and wellness.

Holiday flights don’t have to flatten your energy or your immune system. Dr. Robert Lufkin breaks down what actually happens to your body at altitude—lower oxygen, desert-dry cabins, stalled circulation—and shares a clear plan to stay sharp before, during, and after you fly. Instead of white-knuckling through recycled air and jet lag, you’ll learn how to turn the cabin into a controllable environment and land clear, not crushed.

Cravings aren’t just about weak will; they’re biology doing exactly what billions of food dollars engineered them to do.

We sit down with Dr Nasha Winters to rethink cancer as an ecologic disease and explore how shifting the terrain can change outcomes without rejecting standard care.

That’s the claim at the heart of our conversation with computational neurobiologist and DMT researcher Andrew Gallimore, author of Death by Astonishment.

A facelift without a telltale ear scar sounds like sci‑fi—until you hear how Dr. Mark Mani designed it

Kelly lays out the unvarnished truth about a “miracle cream” millions use and why the industry’s strongest selling points—fast relief and flawless skin—can mask a deeper problem that grows with every tube and refill.

What if you could enjoy all the powerful health benefits of fasting without actually going hungry? Dr. Chris Rhodes, a biochemist with a PhD from UC Davis, has discovered a revolutionary approach that might make this possible.

What if the clothes you wear and the sheets you sleep on could actively improve your health without you doing a thing? In this fascinating conversation, Seth Casden introduces us to a truly passive biohacking tool that’s hiding in plain sight.

What if the secret to treating age-related diseases and extending healthy lifespan lies within tiny cellular structures that evolved from ancient bacteria? In this mind-expanding conversation, biochemist Dr. Natalie Yivgi-Ohana reveals how mitochondria—far more than mere cellular powerhouses—control everything from hormone production to programmed cell death.

Ever wondered how a single molecule can regulate blood flow, support neurotransmission, and boost immune defense?

GLP-1 agonists are transforming medicine in ways few could have predicted. In this captivating conversation, naturopathic physician Dr. Tina Moore challenges the conventional narrative around these medications, revealing their potential beyond weight loss and diabetes management.

Dr. Dominic D’Agostino takes us deep into the science of ketosis, revealing why this evolutionary metabolic state might be the missing link in our modern health crisis.

Guest: Forrest (Kineon) — serial founder bringing clinic-grade photobiomodulation to a safe, wearable form factor.

Cancer isn’t just random genetic mutations. It doesn’t “just happen.” In this episode, Dr. Connealy pulls back the curtain on what really drives cancer — from mitochondrial breakdown and hidden toxins to stress, parasites, and even low voltage inside your cells.

In this episode, Robert Lufkin, MD sits down with Leslie Kenny, a patient advocate with a remarkable story. At 39, she was told she had only 5 years to live with lupus and rheumatoid arthritis. Instead, through lifestyle changes and a breakthrough discovery about spermidine, she now enjoys extraordinary health — with a biological age of just 21 at age 60.

r. Rick Cohen, longevity physician with over 25 years of experience, reveals how this natural molecule discovered on Easter Island targets a fundamental cellular pathway called mTOR that acts as our body’s metabolic switch between growth and repair.